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Article

Autophagy gene expression profiling identifies a defective microtubule-associated protein light chain 3A mutant in cancer.

Oncotarget - 5 Jul 2016

Costa Joana R, Prak Krisna, Aldous Sarah, Gewinner Christina Anja, Ketteler Robin

Abstract excerpt

The cellular stress response autophagy has been implicated in various diseases including neuro-degeneration and cancer. The role of autophagy in cancer is not clearly understood and both tumour promoting and tumour suppressive effects of autophagy have been reported, which complicates the design of therapeutic strategies based on targeting the autophagy pathway. Here, we have systematically analyzed gene...

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Identifiers

PMID: 27256984
DOI: 10.18632/oncotarget.9754
PMCID: PMC5173052

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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