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Article

Statistical inference of a convergent antibody repertoire response to influenza vaccine

25 May 2016

Abstract excerpt

BACKGROUND: Vaccines dramatically affect an individual's adaptive immune system and thus provide an excellent means to study human immunity. Upon vaccination, the B cells that express antibodies (Abs) that happen to bind the vaccine are stimulated to proliferate and undergo mutagenesis at their Ab locus. This process may alter the composition of B cell lineages within an individual, which are known collectively...

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PMID: 27255379
DOI: 10.1186/s13073-016-0314-z

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