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Naturally occurring influenza reassortment in pigs facilitates the emergence of intrahost virus subpopulations with distinct genotypes and replicative fitness.

mBio - 8 Jan 2025

Li Chong, Meliopoulos Victoria, Rendahl Aaron, Schultz-Cherry Stacey, Torremorell Montserrat

Abstract excerpt

Pigs are recognized as amplifying hosts for influenza A virus (IAV) reassortant viruses. Understanding the extent of IAV reassortment occurring at the individual pig level in naturally infected pigs and how reassortment impacts virus diversity, persistence, and replicative fitness is essential for countering IAV threats to humans and animals. Here, 244 IAV plaques were isolated from 24 commercial pigs, resulting...

Topics

Animals
Swine
Reassortant Viruses
Orthomyxoviridae Infections
Genotype
Swine Diseases
Virus Replication
Influenza A virus
Humans
Genome, Viral
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phylogeny

Genetic Fitness

Source

Open in PubMed Open full text

Identifiers

PMID: 39611844
DOI: 10.1128/mbio.01924-24
PMCID: PMC11708028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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