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Article

Comparison of Cox Model Methods in A Low-dimensional Setting with Few Events.

Genomics, proteomics & bioinformatics - 1 Aug 2016

Ojeda Francisco M, Müller Christian, Börnigen Daniela, Trégouët David-Alexandre, Schillert Arne, Heinig Matthias, Zeller Tanja, Schnabel Renate B

Abstract excerpt

Prognostic models based on survival data frequently make use of the Cox proportional hazards model. Developing reliable Cox models with few events relative to the number of predictors can be challenging, even in low-dimensional datasets, with a much larger number of observations than variables. In such a setting we examined the performance of methods used to estimate a Cox model, including (i) full model using...

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Identifiers

PMID: 27224515
DOI: 10.1016/j.gpb.2016.03.006
PMCID: PMC4996851

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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