Article
In vitro rapid diagnostic tests for severe drug hypersensitivity reactions in children.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Jul 2016
Haw Wei Yann, Polak Marta E, McGuire Carolann, Erlewyn-Lajeunesse Michel, Ardern-Jones Michael R
Abstract excerpt
BACKGROUND: Previous reports have demonstrated the utility of T-cell proliferation and cytokine release assays as in vitro diagnostic tests for drug causation in drug hypersensitivity reactions (DHR). However, data from pediatric populations are scarce compared with data in adults. OBJECTIVE: To compare the lymphocyte proliferation assay (LPA) with combination cytokine assays in the pediatric population and to...
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