Article
Genome-wide association study implicates a novel RNA gene, the lincRNA AC068718.1, as a risk factor for post-traumatic stress disorder in women.
Psychoneuroendocrinology - 1 Dec 2013
Guffanti Guia, Galea Sandro, Yan Lulu, Roberts Andrea L, Solovieff Nadia, Aiello Allison E, Smoller Jordan W, De Vivo Immaculata, Ranu Hardeep, Uddin Monica, Wildman Derek E, Purcell Shaun, Koenen Karestan C
Abstract excerpt
Posttraumatic stress disorder (PTSD) is a common and debilitating mental disorder with a particularly high burden for women. Emerging evidence suggests PTSD may be more heritable among women and evidence from animal models and human correlational studies suggest connections between sex-linked biology and PTSD vulnerability, which may extend to the disorder's genetic architecture. We conducted a genome-wide...
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