Article
Regulatory T Cells in Patients with Idiopathic Thrombocytopenic Purpura.
Turkish journal of haematology : official journal of Turkish Society of Haematology - 5 Jun 2016
Akyol Erikçi Alev, Karagöz Bülent, Bilgi Oğuz
Abstract excerpt
OBJECTIVE: Immune thrombocytopenic purpura (ITP) is an immune-mediated bleeding disorder in which platelets are opsonized by autoantibodies and destroyed by an Fc receptor-mediated phagocytosis by the reticuloendothelial system within the spleen. Autoimmune processes are also considered in the pathogenesis of this disorder. CD4+CD25+FoxP3+ regulatory T (Treg) cells and CD8+CD28- Treg cells have roles in...
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