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A systems biology pipeline identifies new immune and disease related molecular signatures and networks in human cells during microgravity exposure

17 May 2016

Abstract excerpt

Microgravity is a prominent health hazard for astronauts, yet we understand little about its effect at the molecular systems level. In this study, we have integrated a set of systems-biology tools and databases and have analysed more than 8000 molecular pathways on published global gene expression datasets of human cells in microgravity. Hundreds of new pathways have been identified with statistical confidence...

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PMID: 27185415
DOI: 10.1038/srep25975

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