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Article

Plasma Acylcarnitines and Amino Acid Levels As an Early Complex Biomarker of Propensity to High-Fat Diet-Induced Obesity in Mice.

PloS one - 1 Jan 2016

Horakova Olga, Hansikova Jana, Bardova Kristina, Gardlo Alzbeta, Rombaldova Martina, Kuda Ondrej, Rossmeisl Martin, Kopecky Jan

Abstract excerpt

Obesity is associated with insulin resistance and impaired glucose tolerance, which represent characteristic features of the metabolic syndrome. Development of obesity is also linked to changes in fatty acid and amino acid metabolism observed in animal models of obesity as well as in humans. The aim of this study was to explore whether plasma metabolome, namely the levels of various acylcarnitines and amino...

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Identifiers

PMID: 27183228
DOI: 10.1371/journal.pone.0155776
PMCID: PMC4868278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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