Article
Biological function derived from predicted structures in CASP11.
Proteins - 1 Sept 2016
Huwe Peter J, Xu Qifang, Shapovalov Maxim V, Modi Vivek, Andrake Mark D, Dunbrack Roland L
Abstract excerpt
In CASP11, the organizers sought to bring the biological inferences from predicted structures to the fore. To accomplish this, we assessed the models for their ability to perform quantifiable tasks related to biological function. First, for 10 targets that were probable homodimers, we measured the accuracy of docking the models into homodimers as a function of GDT-TS of the monomers, which produced characteristic...
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