Article
CX3CR1 polymorphisms associated with an increased risk of developmental dysplasia of the hip in human.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Feb 2017
Li Lianyong, Wang Xi, Zhao Qun, Wang Enbo, Wang Lili, Cheng Jinshan, Zhang Lijun, Wang Binbin
Abstract excerpt
Developmental dysplasia of the hip, also termed congenital hip dislocation, is one of the major causes of children disability and early onset osteoarthritis. Previous study has identified a variant of CX3CR1 underlying this disorder in a large family. However, genetic evidence from population was still lacking. Here, we performed a case-control association study by genotyping two SNPs of CX3CR1, rs3732378, and...
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