Article
Heritability and sibling recurrent risk of developmental dysplasia of the hip in Chinese population.
European journal of clinical investigation - 1 Jun 2013
Li Lianyong, Sun Keming, Zhang Lijun, Zhao Qun, Cheng Xiangjun, Dang Youting
Abstract excerpt
BACKGROUND: Previous familial segregation studies supported that developmental dysplasia of the hip (DDH) is a multifactorial genetic disease. However, the exact extent of genetic effects has not been fully evaluated, especially in Asian population. The aim of this study is to estimate the sibling recurrent risk and heritability of DDH in a large Chinese cohort. MATERIALS AND METHODS: Four hundred and twenty-nine...
Topics
- Case-Control Studies
- China
- Female
- Genetic Predisposition to Disease
- Hip Dislocation, Congenital
- Humans
- Male
- Pedigree
- Prevalence
- Recurrence
- Risk Factors