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Article

The vitamin D receptor gene ApaI polymorphism is associated with increased risk of renal cell carcinoma in Chinese population.

Scientific reports - 13 May 2016

Yang Chunming, Li Jia, Li Yan, Wu Di, Sui Chengguang, Jiang Youhong, Meng Fandong

Abstract excerpt

Molecular epidemiologic studies previously reported that 1,25-dihydroxy vitamin D3 (1,25(OH)2 D3) appears to influence cancer risk. It exerts its activity through the intracellular vitamin D receptor (VDR), which regulates the transcription of genes. This study aimed to investigate the genetic association of VDR polymorphisms with renal cell carcinoma (RCC) risk in the Chinese population. The genotypes of five...

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Source

Open in PubMed Open full text

Identifiers

PMID: 27174575
DOI: 10.1038/srep25987
PMCID: PMC4865864

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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