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Article

Vitamin D receptor gene polymorphisms are associated with increased risk and progression of renal cell carcinoma in a Japanese population.

International journal of urology : official journal of the Japanese Urological Association - 1 Jun 2007

Obara Wataru, Suzuki Yasushi, Kato Karen, Tanji Susumu, Konda Ryuichiro, Fujioka Tomoaki

Abstract excerpt

AIM: Biological and epidemiologic data suggest that 1 alpha, 25 dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) levels may influence development of renal cell carcinoma. The vitamin D receptor (VDR) is a crucial mediator for the cellular effects of 1,25(OH)(2)D(3) and additionally interacts with other cell signaling pathways that influence cancer progression. VDR gene polymorphisms may play an important role in risk of...

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Source

Identifiers

PMID: 17593089
DOI: 10.1111/j.1442-2042.2007.01771.x

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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