Article
Vitamin D receptor gene ApaI polymorphism is associated with susceptibility to colorectal cancer.
Digestive diseases and sciences - 1 Jul 2010
Mahmoudi Touraj, Mohebbi Seyed Reza, Pourhoseingholi Mohamad Amin, Fatemi Seyed Reza, Zali Mohammad Reza
Abstract excerpt
OBJECTIVES: The purpose of this study was to investigate vitamin D receptor (VDR) gene ApaI and TaqI polymorphisms in relation to the risk of colorectal cancer (CRC) in the Iranian population. METHODS: Two single nucleotide polymorphisms in intron 8 (ApaI) and exon 9 (TaqI) of the VDR gene were genotyped in 160 subjects with CRC and 180 controls by use of the PCR-RFLP method. RESULTS: The VDR ApaI genotype...
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