Article
Association of polymorphisms at the microRNA binding site of the caprine KITLG 3'-UTR with litter size.
Scientific reports - 11 May 2016
An Xiaopeng, Song Yuxuan, Bu Shuhai, Ma Haidong, Gao Kexin, Hou Jinxing, Wang Shan, Lei Zhang, Cao Binyun
Abstract excerpt
This study identified three novel single nucleotide polymorphisms (SNPs) (c.1389C > T, c.1457A > C and c.1520G > A) in the caprine KITLG 3'-UTR through DNA sequencing. The three SNP loci were closely linked in Guanzhong dairy (GD) goats. Two alleles of the c.1457A > C SNP introduced two miRNA sites (chi-miR-204-5p and chi-miR-211). Individuals with combined genotype TT-CC-AA had a higher litter size compared with...
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