Article
A Synonymous SNP in DGAT1 Affects Milk Fat Percentage of Dairy Sheep by Regulating the Stability of the mRNA to Change the Viability, Proliferation, and Triglyceride Levels of Ovine Mammary Epithelial Cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 31 Mar 2026
Zhen Huimin, Zhou Huitong, Wang Zike, Li Mingna, Hao Zhiyun, Che Longjie, Ren Chunyan, Wang Jiqing, Wu Xinmiao, Liu Yuan, Hu Jiang, Liu Xiu, Li Shaobin
Abstract excerpt
Diacylglycerol O-acyltransferase1 (DGAT1) is a rate-limiting enzyme that catalyzes triglyceride synthesis originated from diacylglycerol and acyl-CoA. However, there have been no reports on the regulatory mechanism of single nucleotide polymorphisms (SNPs) of DGAT1 underlying lactation performance in sheep. In this study, three SNPs were detected in 476 dairy sheep by Penta-primer Amplification Refractory...
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