Article
Expression of Functional Human Sialyltransferases ST3Gal1 and ST6Gal1 in Escherichia coli.
PloS one - 1 Jan 2016
Ortiz-Soto Maria Elena, Seibel Jürgen
Abstract excerpt
Sialyltransferases (STs) are disulfide-containing, type II transmembrane glycoproteins that catalyze the transfer of sialic acid to proteins and lipids and participate in the synthesis of the core structure oligosaccharides of human milk. Sialic acids are found at the outermost position of glycostructures, playing a key role in health and disease. Sialylation is also essential for the production of recombinant...
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