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Article

Myosin MyTH4-FERM structures highlight important principles of convergent evolution

10 May 2016

Abstract excerpt

Myosins containing MyTH4-FERM (myosin tail homology 4-band 4.1, ezrin, radixin, moesin, or MF) domains in their tails are found in a wide range of phylogenetically divergent organisms, such as humans and the social amoeba Dictyostelium (Dd). Interestingly, evolutionarily distant MF myosins have similar roles in the extension of actin-filled membrane protrusions such as filopodia and bind to microtubules (MT),...

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PMID: 27166421
DOI: 10.1073/pnas.1600736113

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