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Article

Is Isolated Low High-Density Lipoprotein Cholesterol a Cardiovascular Disease Risk Factor? New Insights From the Framingham Offspring Study.

Circulation. Cardiovascular quality and outcomes - 1 May 2016

Bartlett Jacquelaine, Predazzi Irene M, Williams Scott M, Bush William S, Kim Yeunjung, Havas Stephen, Toth Peter P, Fazio Sergio, Miller Michael

Abstract excerpt

BACKGROUND: Although the inverse association between high-density lipoprotein cholesterol (HDL-C) and risk of cardiovascular disease (CVD) has been long established, it remains unclear whether low HDL-C remains a CVD risk factor when levels of low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG) are not elevated. This is a timely issue because recent studies have questioned whether HDL-C is truly an...

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Identifiers

PMID: 27166203
DOI: 10.1161/CIRCOUTCOMES.115.002436
PMCID: PMC4871717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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