Article
The inverted pattern of circulating miR-221-3p and miR-222-3p associated with isolated low HDL-C phenotype.
Lipids in health and disease - 16 Aug 2018
Zhou Yuntao, Liu Mengdi, Li Jinrong, Wu Bing, Tian Wei, Shi Lu, Zhang Jing, Sun Zening
Abstract excerpt
BACKGROUND: We investigated the baseline characterization of cardiovascular disease (CVD)-derived circulating miR-221-3p/222-3p in isolated low HDL-C phenotype (ILHP) to enhance our understanding on their molecular pathological pattern prior to disease onset. METHODS: We screened 174 asymptomatic subjects with isolated low HDL-C phenotype (n = 88) and normal lipid phenotype (n = 86), and detected circulating...
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