Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CXCL10 Acts as a Bifunctional Antimicrobial Molecule against Bacillus anthracis.

mBio - 10 May 2016

Margulieux Katie R, Fox Jay W, Nakamoto Robert K, Hughes Molly A

Abstract excerpt

UNLABELLED: Bacillus anthracis is killed by the interferon-inducible, ELR(-) CXC chemokine CXCL10. Previous studies showed that disruption of the gene encoding FtsX, a conserved membrane component of the ATP-binding cassette transporter-like complex FtsE/X, resulted in resistance to CXCL10. FtsX exhibits some sequence similarity to the mammalian CXCL10 receptor, CXCR3, suggesting that the CXCL10 N-terminal region...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacillus anthracis
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Cycle Proteins

Share to Chemokine CXCL10

Share to Membrane Potentials

Share to Protein Binding

Share to Sequence Alignment

Source

Open in PubMed Open full text

Identifiers

PMID: 27165799
DOI: 10.1128/mBio.00334-16
PMCID: PMC4959661

Genes

CXCL10
CXCR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

CXCL10 Acts as a Bifunctional Antimicrobial Molecule against Bacillus anthracis.PMID 27165799Read ↗

Identification of the bacterial protein FtsX as a unique target of chemokine-mediated antimicrobial activity against Bacillus anthracis.Semantic proximity Read ↗

The Opp (AmiACDEF) Oligopeptide Transporter Mediates Resistance of Serotype 2 Streptococcus pneumoniae D39 to Killing by Chemokine CXCL10 and Other Antimicrobial Peptides.Semantic proximity Read ↗

Contribution of lethal toxin and edema toxin to the pathogenesis of anthrax meningitis.Semantic proximity Read ↗

Therapeutic potential of FtsZ inhibition: a patent perspectiveSemantic proximity Read ↗

Cross-talk between intracellular pathogen infection and IFNγ signaling drives enhanced pro-inflammatory responsesSemantic proximity Read ↗

The <i>Bacillus anthracis</i> Protein MprF Is Required for Synthesis of Lysylphosphatidylglycerols and for Resistance to Cationic Antimicrobial PeptidesSemantic proximity Read ↗

Structure of the large extracellular loop of FtsX and its interaction with the essential peptidoglycan hydrolase PcsB in <i>Streptococcus pneumoniae</i>Semantic proximity Read ↗

Infect and Inject: How Mycobacterium tuberculosis Exploits Its Major Virulence-Associated Type VII Secretion System, ESX-1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.