Article
Analysis of crystal structure of Arabidopsis MPK6 and generation of its mutants with higher activity.
Scientific reports - 10 May 2016
Wang Bo, Qin Xinghua, Wu Juan, Deng Hongying, Li Yuan, Yang Hailian, Chen Zhongzhou, Liu Guoqin, Ren Dongtao
Abstract excerpt
Mitogen-activated protein kinase (MAPK) cascades, which are the highly conserved signalling modules in eukaryotic organisms, have been shown to play important roles in regulating growth, development, and stress responses. The structures of various MAPKs from yeast and animal have been solved, and structure-based mutants were generated for their function analyses, however, the structures of plant MAPKs remain...
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