Article
The MKK2 pathway mediates cold and salt stress signaling in Arabidopsis.
Molecular cell - 2 Jul 2004
Teige Markus, Scheikl Elisabeth, Eulgem Thomas, Dóczi Róbert, Ichimura Kazuya, Shinozaki Kazuo, Dangl Jeffery L, Hirt Heribert
Abstract excerpt
The Arabidopsis mitogen-activated protein kinase (MAPK) kinase 2 (MKK2) and the downstream MAPKs MPK4 and MPK6 were isolated by functional complementation of osmosensitive yeast mutants. In Arabidopsis protoplasts, MKK2 was specifically activated by cold and salt stress and by the stress-induced MAPK kinase kinase MEKK1. Yeast two-hybrid, in vitro, and in vivo protein kinase assays revealed that MKK2 directly...
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