Article
MEK5 overexpression is associated with the occurrence and development of colorectal cancer.
BMC cancer - 9 May 2016
Diao Dechang, Wang Lei, Wan Jin, Chen Zhiqiang, Peng Junsheng, Liu Huanliang, Chen Xinlin, Wang Wei, Zou Liaonan
Abstract excerpt
BACKGROUND: Mitogen/extracellular signal-regulated kinase kinase-5 (MEK5) has been confirmed to play a pivotal role in tumor carcinogenesis and progression. However, few studies have investigated the role of MEK5 in colorectal cancer (CRC). METHODS: MEK5 expression was determined by immunohistochemistry (IHC) in tissue microarrays (TMAs) containing 2 groups of tissues, and western blotting was used to confirm...
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