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Article

Modulation of Osteogenesis in MC3T3-E1 Cells by Different Frequency Electrical Stimulation

5 May 2016

Abstract excerpt

Electrical stimulation (ES) is therapeutic to many bone diseases, from promoting fracture regeneration to orthopedic intervention. The application of ES offers substantial therapeutic potential, while optimal ES parameters and the underlying mechanisms responsible for the positive clinical impact are poorly understood. In this study, we assembled an ES cell culture and monitoring device. Mc-3T3-E1 cells were...

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PMID: 27149625
DOI: 10.1371/journal.pone.0154924

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