Article
Subtypes of atopic dermatitis: From phenotype to endotype.
Allergology international : official journal of the Japanese Society of Allergology - 1 Jan 2022
Tokura Yoshiki, Hayano Satoshi
Abstract excerpt
Atopic dermatitis (AD) is a heterogenous disorder and can be classified into different types. Stratification of subtypes may enable personalized medicine approaches. AD can be categorized into the IgE-high, extrinsic subtype and the IgE-normal, intrinsic subtype. While extrinsic AD is the major subtype possessing skin barrier impairment (high incidence of filaggrin mutations), intrinsic AD occupies about 20% of...
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