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Article

Imbalanced expression of dysfunctional regulatory T cells and T-helper cells relates to immunopathogenesis in polyarteritis nodosa.

Modern rheumatology - 1 Jan 2017

Shimojima Yasuhiro, Ishii Wataru, Kishida Dai, Fukushima Kazuhiro, Ikeda Shu-Ichi

Abstract excerpt

OBJECTIVES: We investigated the characteristics of circulating T-helper (Th) cells and CD4+ regulatory T cells (Tregs) in polyarteritis nodosa (PAN). METHODS: Peripheral blood samples were obtained from 14 patients with PAN. Nine patients having granulomatosis with polyangiitis (GPA) and 11 healthy individuals (HC) were enrolled as controls. Th cells and Tregs were analyzed by flow cytometry. Suppression assay of...

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Identifiers

PMID: 27142840
DOI: 10.3109/14397595.2016.1172999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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