Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

β1 Tubulin Rather Than β2 Tubulin Is the Preferred Binding Target for Carbendazim in Fusarium graminearum.

Phytopathology - 1 Sept 2016

Zhou Yujun, Zhu Yuanye, Li Yanjun, Duan Yabing, Zhang Rongsheng, Zhou Mingguo

Abstract excerpt

Tubulins are the proposed target of anticancer drugs, anthelminthics, and fungicides. In Fusarium graminearum, β2 tubulin has been reported to be the binding target of methyl benzimidazole carbamate (MBC) fungicides. However, the function of F. graminearum β1 tubulin, which shares 76% amino acid sequence identity with β2 tubulin, in MBC sensitivity has been unclear. In this study, MBC sensitivity relative to that...

Topics

Amino Acid Sequence
Antibody Specificity
Benzimidazoles
Carbamates
Fungal Proteins
Fungicides, Industrial
Fusarium
Genes, Reporter
Microtubules
Mutation
Plant Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Recombinant Fusion Proteins

Sequence Alignment

Tubulin

Source

Identifiers

PMID: 27135676
DOI: 10.1094/PHYTO-09-15-0235-R

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

β1 Tubulin Rather Than β2 Tubulin Is the Preferred Binding Target for Carbendazim in Fusarium graminearum.PMID 27135676Read ↗

Detrimental Effects of Multiple Mutations in Position 240 of Fusarium graminearum β2-Tubulin.Semantic proximity Read ↗

Mutations in a beta-tubulin confer resistance of Gibberella zeae to benzimidazole fungicides.Semantic proximity Read ↗

Localisation of the benzimidazole fungicide binding site of Gibberella zeae β2-tubulin studied by site-directed mutagenesis.Semantic proximity Read ↗

Involvement of FgMad2 and FgBub1 in regulating fungal development and carbendazim resistance in Fusarium graminearumSemantic proximity Read ↗

Detection and molecular characterisation of Pyrenopeziza brassicae isolates resistant to methyl benzimidazole carbamates.Semantic proximity Read ↗

Molecular mechanism of resistance of Fusarium fujikuroi to benzimidazole fungicides.Semantic proximity Read ↗

Dual Impact of a Benzimidazole Resistant β-Tubulin on Microtubule Behavior in Fission Yeast.Semantic proximity Read ↗

Molecular evolution and functional divergence of tubulin superfamily in the fungal tree of life.Semantic proximity Read ↗

Identification of key interactions of benzimidazole resistance-associated amino acid mutations in Ascaris β-tubulins by molecular docking simulations.Semantic proximity Read ↗

Novel point mutations in β-tubulin gene for carbendazim resistance maintaining nematode pathogenicity of Paecilomyces lilacinusSemantic proximity Read ↗

Identification of Key Interactions of Benzimidazole Resistance-Associated Amino Acid Mutations in Ascaris β-Tubulins By Molecular Docking SimulationsSemantic proximity Read ↗

Identification of key interactions of benzimidazole resistance-associated amino acid mutations in <i>Ascaris</i> β-tubulins by molecular docking simulationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.