Article
Cross Talk Mechanism among EMT, ROS, and Histone Acetylation in Phorbol Ester‐Treated Human Breast Cancer MCF‐7 Cells
1 Jan 2016
Abstract excerpt
Epithelial-mesenchymal transition (EMT) plays a pivotal role in the progression of cancer, and some transcription factors including Slug and Snail are known to be involved in EMT processes. It has been well established that the excess production of reactive oxygen species (ROS) and epigenetics such as DNA methylation and histone modifications participate in carcinogenesis; however, the cross talk mechanism among...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
