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Diagnostic Accuracy of FISH and RT-PCR in 50 Routinely Processed Synovial Sarcomas

18 Apr 2008

Abstract excerpt

BACKGROUND: Molecular detection of SYT-SSX fusion genes is the most reliable tool for diagnosing synovial sarcoma (SS). The objective of this study was to investigate the accuracy of reverse transcription-polymerase chain reaction (RT-PCR) and a commercially available fluorescence in situ hybridization (FISH) technique for formalin-fixed and paraffin-embedded tumor tissue. PATIENTS AND METHODS: Fifty tumors with...

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PMID: 18301245
DOI: 10.1097/pai.0b013e31815349f5

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