Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An examination of the regulatory mechanism of Pxdn mutation-induced eye disorders using microarray analysis.

International journal of molecular medicine - 1 Jun 2016

Yang Yang, Xing Yiqiao, Liang Chaoqun, Hu Liya, Xu Fei, Mei Qi

Abstract excerpt

The present study aimed to identify biomarkers for peroxidasin (Pxdn) mutation-induced eye disorders and study the underlying mechanisms involved in this process. The microarray dataset GSE49704 was used, which encompasses 4 mouse samples from embryos with Pxdn mutation and 4 samples from normal tissues. After data preprocessing, the differentially expressed genes (DEGs) between Pxdn mutation and normal tissues...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclin-Dependent Kinase Inhibitor p27
Share to Extracellular Matrix Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forkhead Transcription Factors

Share to Glaucoma

Share to Microarray Analysis

Share to Peroxidase

Share to Protein Interaction Mapping

Source

Open in PubMed Open full text

Identifiers

PMID: 27121343
DOI: 10.3892/ijmm.2016.2572
PMCID: PMC4866968

Genes

FOXO4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An examination of the regulatory mechanism of Pxdn mutation-induced eye disorders using microarray analysis.PMID 27121343Read ↗

Peroxidasin is essential for eye development in the mouse.Semantic proximity Read ↗

RNA-Seq reveals differential expression profiles and functional annotation of genes involved in retinal degeneration in Pde6c mutant Danio rerioSemantic proximity Read ↗

Prediction of Differentially Expressed miRNAs as Potential Biomarkers for Aniridia-Associated Keratopathy based on Expression Profile AnalysesSemantic proximity Read ↗

Identification of regulatory genes associated with POAG by integrating expression and sequencing data.Semantic proximity Read ↗

RNA-Seq reveals differential expression profiles and functional annotation of genes involved in retinal degeneration in Pde6c mutant Danio rerio.Semantic proximity Read ↗

Integrative RNA-seq and ATAC-seq analyses of phosphodiesterase 6 mutation-induced retinitis pigmentosa.Semantic proximity Read ↗

Integrated aqueous humor ceRNA and miRNA-TF-mRNA network analysis reveals potential molecular mechanisms governing primary open-angle glaucoma pathogenesisSemantic proximity Read ↗

Effects of destrin pathway mutations on the gene expression profile.Semantic proximity Read ↗

Identification of genes asscoiated with pyroptosis in Age-related cataract of using bioinformatics analysesSemantic proximity Read ↗

Computational analysis of tissue-specific gene networks: application to murine retinal functional studiesSemantic proximity Read ↗

Analysis of Transcriptional Regulatory Pathways of Photoreceptor Genes by Expression Profiling of the Otx2-Deficient RetinaSemantic proximity Read ↗

Analysis of gene network bifurcation during optic cup morphogenesis in zebrafishSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.