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Article

Increased Expression of Ubiquitin-Specific Protease 4 Participates in Neuronal Apoptosis After Intracerebral Hemorrhage in Adult Rats.

Cellular and molecular neurobiology - 1 Apr 2017

Liu Chao, Liu Chun, Liu Hanzhang, Gong Leilei, Tao Tao, Shen Yifen, Zhu Shunxing, Shen Aiguo

Abstract excerpt

Ubiquitinating enzymes catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzyme (DUB) action. Ubiquitin-specific protease 4 (USP4) is a member of the ubiquitin-specific protease (USP) family of DUBs that has a role in spliceosome regulation. In the present study, we demonstrated that USP4 may be involved in neuronal apoptosis in the processes of intracerebral hemorrhage (ICH). We...

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Source

Identifiers

PMID: 27114249
DOI: 10.1007/s10571-016-0375-y

Genes

USP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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