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Article

Comparative genomic hybridization in detection of DNA changes in canine lymphomas.

Animal science journal = Nihon chikusan Gakkaiho - 1 Jan 2017

Drážovská Monika, Šiviková Katarína, Dianovský Ján, Horňák Miroslav

Abstract excerpt

In this study, chromosomal imbalances in tumor tissues (lymphomas) and nucleotide changes in tumor suppressor TP53 were studied in a Bernese Mountain dog bitch and a cross breed bitch. Using comparative genomic hybridization, numerous chromosomal rearrangements were detected, which indicated the heterogeneity in tumor growth: in the cross breed bitch, a deletion on the chromosome 9, and duplications on...

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PMID: 27112539
DOI: 10.1111/asj.12582

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