Article
Interaction between 25-hydroxyvitamin D and variants at 17q12-21 on respiratory infections.
Pediatric pulmonology - 1 Sept 2016
Sheen Youn Ho, Lee Eun, Kang Mi-Jin, Yu Ho-Sung, Ahn Kangmo, Kim Kyung Won, Yang Song-I, Jung Young-Ho, Lee Kyung-Ju, Chang Hyoung Yoon, Shin Hye Lim, Choi Kil Yong, Kim Hyung Young, Seo Ju-Hee, Kwon Ji-Won, Kim Byoung-Ju, Kim Hyo-Bin, Lee So-Yeon, Suh Dong In, Yang Hyeon-Jong, Choi Suk-Joo, Oh Soo-Young, Kwon Ja-Young, Kim Soo Hyun, Won Hye-Sung, Kim Eun-Jin, Lee Jeom Kyu, Hong Soo-Jong
Abstract excerpt
OBJECTIVES: 25-hydroxyvitamin D (25[OH]D) deficiency and genetic variants at the 17q12-21 locus are independent risk factors for respiratory tract infections (RTIs). We aimed to investigate whether the effect of 25(OH)D at birth and 1 year of age and the polymorphism at the 17q12-21 locus, or interactions between these two factors, increase susceptibility to RTIs in the first year of life. METHODS: We tested...
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