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Article

Low Vitamin-D Levels Combined with PKP3-SIGIRR-TMEM16J Host Variants Is Associated with Tuberculosis and Death in HIV-Infected and -Exposed Infants.

PloS one - 1 Jan 2016

Gupta Amita, Montepiedra Grace, Gupte Akshay, Zeldow Bret, Jubulis Jennifer, Detrick Barbara, Violari Avy, Madhi Shabir, Bobat Raziya, Cotton Mark, Mitchell Charles, Spector Stephen

Abstract excerpt

BACKGROUND: This study examined the associations of 25-hydroxyvitamin D and specific host genetic variants that affect vitamin D levels or its effects on immune function, with the risk of TB or mortality in children. METHODS: A case-cohort sample of 466 South African infants enrolled in P1041 trial (NCT00080119) underwent 25-hydroxyvitamin D testing by chemiluminescent immunoassay. Single nucleotide polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Interleukin-1

Share to Tuberculosis, Pulmonary

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Source

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Identifiers

PMID: 26872154
DOI: 10.1371/journal.pone.0148649
PMCID: PMC4752266

Genes

PKP3
SIGIRR
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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