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Article

ETS transcription factor ERG cooperates with histone demethylase KDM4A

15 Apr 2016

Abstract excerpt

ERG (ETS-related gene) is a member of the ETS (erythroblast transformation-specific) family of transcription factors. Overexpression of the ERG transcription factor is observed in half of all prostate tumors and is an underlying cause of this disease. However, the mechanisms involved in the functions of ERG are still not fully understood. In the present study, we showed that ERG can directly bind to KDM4A (also...

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Identifiers

PMID: 27109047
DOI: 10.3892/or.2016.4747

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