Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ERG Induces Epigenetic Activation of Tudor Domain-Containing Protein 1 (TDRD1) in ERG Rearrangement-Positive Prostate Cancer

29 Mar 2013

Abstract excerpt

BACKGROUND: Overexpression of ERG transcription factor due to genomic ERG-rearrangements defines a separate molecular subtype of prostate tumors. One of the consequences of ERG accumulation is modulation of the cell's gene expression profile. Tudor domain-containing protein 1 gene (TDRD1) was reported to be differentially expressed between TMPRSS2:ERG-negative and TMPRSS2:ERG-positive prostate cancer. The aim of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Mechanisms of cancer metastasis
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23555854
DOI: 10.1371/journal.pone.0059976

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ERG Induces Epigenetic Activation of Tudor Domain-Containing Protein 1 (TDRD1) in ERG Rearrangement-Positive Prostate CancerPMID 23555854Read ↗

Identification of TDRD1 as a direct target gene of ERG in primary prostate cancerSemantic proximity Read ↗

ETS transcription factor ERG cooperates with histone demethylase KDM4ASemantic proximity Read ↗

The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer BiomarkerSemantic proximity Read ↗

Epigenomic profiling of prostate cancer identifies differentially methylated genes in TMPRSS2:ERG fusion-positive versus fusion-negative tumorsSemantic proximity Read ↗

Molecular Subtyping of Primary Prostate Cancer Reveals Specific and Shared Target Genes of Different ETS RearrangementsSemantic proximity Read ↗

Transcriptional network involving ERG and AR orchestrates Distal-Less Homeobox 1 mediated prostate cancer progressionSemantic proximity Read ↗

Distinct genomic aberrations associated with ERG rearranged prostate cancerSemantic proximity Read ↗

Transcriptional network involving ERG and AR orchestrates Distal-Less Homeobox 1 mediated prostate cancer progressionSemantic proximity Read ↗

Transcriptional network involving ERG and AR orchestrates Distal-less homeobox-1 mediated prostate cancer progressionSemantic proximity Read ↗

ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis.Semantic proximity Read ↗

ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor.Semantic proximity Read ↗

EZH2-induced lysine K362 methylation enhances TMPRSS2-ERG oncogenic activity in prostate cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.