Sarcoidosis--scientific progress and clinical challenges.

doi:10.1038/nrrheum.2011.93

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Article

Sarcoidosis--scientific progress and clinical challenges.

Nature reviews. Rheumatology - 12 Jul 2011

Chen Edward S, Moller David R

Abstract excerpt

Sarcoidosis is an uncommon systemic inflammatory disorder characterized by noncaseating granulomatous inflammation that most commonly affects the lungs, intrathoracic lymph nodes, eyes and skin. One-third or more of patients with sarcoidosis have chronic, unremitting inflammation with progressive organ impairment. Findings of family and genetic studies indicate a genetic susceptibility to sarcoidosis, with genes...

Topics

Bacterial Infections
Genetic Predisposition to Disease
Glucocorticoids
Humans
Prognosis
Sarcoidosis

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Open in PubMed

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PMID: 21750528
DOI: 10.1038/nrrheum.2011.93

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