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Article

Mechanism of Action of Secreted Newt Anterior Gradient Protein.

PloS one - 1 Jan 2016

Grassme Kathrin S, Garza-Garcia Acely, Delgado Jean-Paul, Godwin James W, Kumar Anoop, Gates Phillip B, Driscoll Paul C, Brockes Jeremy P

Abstract excerpt

Anterior gradient (AG) proteins have a thioredoxin fold and are targeted to the secretory pathway where they may act in the ER, as well as after secretion into the extracellular space. A newt member of the family (nAG) was previously identified as interacting with the GPI-anchored salamander-specific three-finger protein called Prod1. Expression of nAG has been implicated in the nerve dependence of limb...

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Source

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Identifiers

PMID: 27100463
DOI: 10.1371/journal.pone.0154176
PMCID: PMC4839744

Genes

AGR2
GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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