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Article

Differential gene expression in porcine SK6 cells infected with wild-type and SAP domain-mutant foot-and-mouth disease virus.

Virologica Sinica - 1 Jun 2016

Ni Zixin, Yang Fan, Cao Weijun, Zhang Xiangle, Jin Ye, Mao Ruoqing, Du Xiaoli, Li Weiwei, Guo Jianhong, Liu Xiangtao, Zhu Zixiang, Zheng Haixue

Abstract excerpt

Foot-and-mouth disease virus (FMDV) is the causative agent of a highly contagious disease in livestock. The viral proteinase L(pro) of FMDV is involved in pathogenicity, and mutation of the L(pro) SAP domain reduces FMDV pathogenicity in pigs. To determine the gene expression profiles associated with decreased pathogenicity in porcine cells, we performed transcriptome analysis using next-generation sequencing...

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Identifiers

PMID: 27097918
DOI: 10.1007/s12250-015-3709-x
PMCID: PMC8193384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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