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Aberrant host immune response induced by highly virulent PRRSV identified by digital gene expression tag profiling

7 Oct 2010

Abstract excerpt

BACKGROUND: There was a large scale outbreak of the highly pathogenic porcine reproductive and respiratory syndrome (PRRS) in China and Vietnam during 2006 and 2007 that resulted in unusually high morbidity and mortality among pigs of all ages. The mechanisms underlying the molecular pathogenesis of the highly virulent PRRS virus (H-PRRSV) remains unknown. Therefore, the relationship between pulmonary gene...

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PMID: 20929578
DOI: 10.1186/1471-2164-11-544

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