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Article

Effect of ABCB1 rs12720464 and rs1055302 polymorphisms in Chinese patients on the time course of action of rocuronium administered as a single dose.

International journal of clinical pharmacology and therapeutics - 1 Jun 2016

Qi Tian-long, Zhou Yin-hui, Yuan Jing-jing, Li Zhi-song, Wang Zhong-yu, Chang Yan-zi, Zhao Er-xian, Cheng Dan, Hou Jun-kai, Tian Yan, Chen Ge-zi, Mao Yuan-yuan, Ren Yang, Zhang Li-rong, Kan Quan-cheng, Zhang Wei

Abstract excerpt

OBJECTIVE: To determine whether ABCB1 gene polymorphisms affect the time course of action of rocuronium in Chinese patients. METHODS: This study included 105 unrelated Chinese patients undergoing general anesthesia with propofol, fentanyl, and rocuronium. Neuromuscular monitoring was performed with calibrated acceleromyography. Patients were allowed to recover spontaneously from the neuromuscular block. The time...

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Identifiers

PMID: 27087154
DOI: 10.5414/CP202547

Genes

ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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