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Article

Role of SLCO1B1, ABCB1, and CHRNA1 gene polymorphisms on the efficacy of rocuronium in Chinese patients.

Journal of clinical pharmacology - 1 Mar 2015

Mei Yang, Wang Sai-Ying, Li Yang, Yi Shuang-Qiang, Wang Chun-Yan, Yang Mi, Duan Kai-Ming

Abstract excerpt

This study explored the role of SLCO1B1, ABCB1, and CHRNA1 gene polymorphisms on the efficacy and duration of action of rocuronium in Chinese patients. Two hundred seven unrelated Chinese patients scheduled for elective surgery were recruited, and 200 completed the study. Their ABCB1, SLCO1B1, and CHRNA1 genotypes were determined. Demographic and clinical non-genetic data also were collected. The SLCO1B1, ABCB1,...

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Source

Identifiers

PMID: 25279974
DOI: 10.1002/jcph.405

Genes

ABCB1
CHRNA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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