Article
Sequence analysis of the L protein of the Ebola 2014 outbreak: Insight into conserved regions and mutations.
Molecular medicine reports - 1 Jun 2016
Ayub Gohar, Waheed Yasir
Abstract excerpt
The 2014 Ebola outbreak was one of the largest that have occurred; it started in Guinea and spread to Nigeria, Liberia and Sierra Leone. Phylogenetic analysis of the current virus species indicated that this outbreak is the result of a divergent lineage of the Zaire ebolavirus. The L protein of Ebola virus (EBOV) is the catalytic subunit of the RNA‑dependent RNA polymerase complex, which, with VP35, is key for...
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