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Article

Identification of novel BRCA founder mutations in Middle Eastern breast cancer patients using capture and Sanger sequencing analysis.

International journal of cancer - 1 Sept 2016

Bu Rong, Siraj Abdul K, Al-Obaisi Khadija A S, Beg Shaham, Al Hazmi Mohsen, Ajarim Dahish, Tulbah Asma, Al-Dayel Fouad, Al-Kuraya Khawla S

Abstract excerpt

Ethnic differences of breast cancer genomics have prompted us to investigate the spectra of BRCA1 and BRCA2 mutations in different populations. The prevalence and effect of BRCA 1 and BRCA 2 mutations in Middle Eastern population is not fully explored. To characterize the prevalence of BRCA mutations in Middle Eastern breast cancer patients, BRCA mutation screening was performed in 818 unselected breast cancer...

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Source

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Identifiers

PMID: 27082205
DOI: 10.1002/ijc.30143
PMCID: PMC5111783

Genes

BRCA1
BRCA2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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