Article
T-Cell Epitope Discovery for Therapeutic Cancer Vaccines.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016
Krishna Sri, Anderson Karen S
Abstract excerpt
The success of recent immune checkpoint blockade trials in solid tumors has demonstrated the tremendous potential of immune-mediated treatment strategies for cancer therapy. These immune therapies activate preexisting cytotoxic CD8(+) T cells (CTL) to selectively target and eradicate malignant cells. In vitro models suggest that these therapies may be more effective in combination with priming of CTL using cancer...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
