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Targeting Host Factors to Treat West Nile and Dengue Viral Infections

10 Feb 2014

Abstract excerpt

West Nile (WNV) and Dengue (DENV) viruses are major arboviral human pathogens belonging to the genus Flavivirus. At the current time, there are no approved prophylactics (e.g., vaccines) or specific therapeutics available to prevent or treat human infections by these pathogens. Due to their minimal genome, these viruses require many host molecules for their replication and this offers a therapeutic avenue wherein...

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PMID: 24517970
DOI: 10.3390/v6020683

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