Article
Long Noncoding RNAs in Cancer Pathways.
Cancer cell - 11 Apr 2016
Schmitt Adam M, Chang Howard Y
Abstract excerpt
Genome-wide cancer mutation analyses are revealing an extensive landscape of functional mutations within the noncoding genome, with profound effects on the expression of long noncoding RNAs (lncRNAs). While the exquisite regulation of lncRNA transcription can provide signals of malignant transformation, we now understand that lncRNAs drive many important cancer phenotypes through their interactions with other...
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