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Article

The bright side of dark matter: lncRNAs in cancer.

The Journal of clinical investigation - 1 Aug 2016

Evans Joseph R, Feng Felix Y, Chinnaiyan Arul M

Abstract excerpt

The traditional view of genome organization has been upended in the last decade with the discovery of vast amounts of non-protein-coding transcription. After initial concerns that this "dark matter" of the genome was transcriptional noise, it is apparent that a subset of these noncoding RNAs are functional. Long noncoding RNA (lncRNA) genes resemble protein-coding genes in several key aspects, and they have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27479746
DOI: 10.1172/JCI84421
PMCID: PMC4966302

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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